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Mefloquine: what is it, what is it for and secondary effects

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Mefloquina is a drug indicated to prevent malaria (malaria), in people who intend to travel to areas where there is a greater risk of developing this disease. In addition, it can also be used for the treatment of malaria caused by certain agents, when combined with another drug, called artesunate

Mefloquine is available in pharmacies and can only be purchased through the presentation of a medical prescription.

Mefloquine is indicated for the prevention of malaria in people who intend to travel to endemic areas, and when combined with artesunate, it can be used to treat malaria caused by certain agents.



Is mefloquine indicated for the treatment of coronavirus infection?

The use of mefloquine for the treatment of the new coronavirus infection, however, is not recommended, although it has shown promising results in the treatment of COVID-19[1]more studies are needed to verify its effectiveness and security.

In addition, in Russia, however, a possibly effective treatment regimen is being tested, with mefloquine combined with other drugs, but with no conclusive results.

Self-medication with mefloquina is inadvisable and dangerous, and can have serious consequences for health.

This medication should be taken orally, enterally and with a water bottle during meals. The dose must be determined by the doctor depending on the specific illness, seriousness and individual response to the medication. For the treatment of children, the doctor must adjust the dose to their weight.



For adults, when mefloquine is used for malaria prevention, it is recommended to start treatment about 2 to 3 weeks before travel. Therefore, 1 tablet of 250 mg per week must be administered, always maintaining this regimen until 4 weeks after the return.

If it is not possible to start preventive treatment with anticipation, mefloquine can be started a week before the trip, however, it is important to know that serious adverse events usually occur until the third dose, having the possibility that they occur during the trip. Alternatively, mefloquine can be used in a loading dose of 750 mg as a single dose and then start the regimen with 250 mg weekly.

Know how to identify the symptoms of malaria and what to do.

Mefloquine acts on the asexual life cycle of the parasite, which occurs within the blood cells, through the formation of complexes with the blood group, preventing the inactivation of these by the parasite. The complexes formed and the free hemogroup are toxic to the parasite.

Mefloquine does not exercise activity against hepatic forms of the parasite, nor against its sexual forms.

Mefloquine is contraindicated for people with hypersensitivity to the components of the formula, for children weighing less than 5 kg or less than 6 months, pregnant women and during lactation.

In addition, it should not be used in people with kidney and liver problems, history of recent therapy with halofantrine, history of psychiatric illness, such as depression, bipolar affective disorder or severe anxiety neurosis and epilepsy.

Some of the side effects that may occur during treatment with mefloquine are nausea, headache, nausea, abdominal pain and diarrhea.

In addition, even when it is more rare, insomnia, hallucinations, changes in coordination, mood changes, agitation, aggression and paranoid reactions can also occur.

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Consult a Doctor | Translated by User2937

Content for educational purposes only

The translator user relied on the following text:

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Disclaimer – (English version>) This content has been prepared based on information from research, additional publications, or the translation/verification work of a volunteer editor of this web council. This is a non-profit service. It is strongly recommended that all details and information published be carefully verified. We never allow medication recommendations, medication package inserts or any medication guidance. We never allow partisan politics as information.

Isenção de responsabilidade – (versão em português): Este conteúdo foi preparado com base em informações de pesquisas, publicações adicionais ou no trabalho de tradução/verificação de um editor voluntário deste conselho web. Este é um serviço sem fins lucrativos. É altamente recomendável que todos os detalhes e informações publicadas sejam verificadas cuidadosamente. Nunca permitimos recomendações de medicamentos, bulas ou qualquer orientação sobre medicamentos. Nunca permitimos a política partidária como base para checagem. Para mais informações, leia nossos termos.

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